Glycine is an amino acid that plays a crucial role in the health of joints, cartilage, tissues, and muscles. Although it is a non-essential amino acid, meaning the body can produce it, it performs numerous vital functions essential for the proper functioning of the body. Glycine’s role spans from protecting joints and cartilage to supporting muscle building, making it a key player in maintaining a healthy musculoskeletal system.
One of glycine’s most important functions is promoting muscle tissue formation by converting glucose into energy that fuels muscle cells. About one-third of the protein in collagen consists of glycine. To ensure proper cellular function, glycine contributes to the formation of healthy DNA strands. It also minimizes liver damage by helping absorb foreign substances, toxins, or alcohol.
A major role of glycine lies in the production of collagen and gelatin. These substances are fundamental to the proper function of joints, tendons, and ligaments, as they provide elasticity and strength. Collagen contains a significant amount of glycine, making this amino acid essential for the proper functioning and regeneration of connective tissues. Furthermore, glycine helps prevent the breakdown of valuable proteins, promotes muscle growth, and supports muscle recovery, thereby aiding a healthy muscular system and an active lifestyle.
Glycine also plays a significant role in digestive health. By supporting the production of collagen and gelatin, it helps maintain the integrity and protection of digestive system tissues, preventing issues such as leaky gut syndrome and other gastrointestinal problems. Additionally, glycine aids in the production of digestive enzymes and bile acids necessary for effective nutrient breakdown and absorption.
With its antioxidant properties, glycine protects cells from damage and aging. By contributing to the production of glutathione, it helps prevent oxidative stress-induced damage, promoting healthy cell function and reducing signs of aging. Research shows that glycine plays an important role in both digestive and central nervous system functions, which are vital for maintaining a healthy, youthful body.
Methionine, an essential amino acid that the body cannot produce and must be obtained through diet, is often consumed in excess, particularly in high-methionine animal-based proteins. Excess methionine intake can lead to the production of homocysteine, a compound that damages the inner walls of blood vessels, increasing the risk of atherosclerosis and other cardiovascular issues. This can accelerate aging processes and contribute to health problems. Glycine has the ability to limit methionine absorption, thereby reducing homocysteine levels in the body. Studies suggest that restricting methionine intake or mitigating its effects—such as through glycine consumption—may lead to longer lifespans and healthier aging. While human studies have yet to confirm these effects conclusively, animal research has shown promising results.
Research also indicates that glycine can be used to reduce liver damage caused by alcohol and other acute or chronic liver injuries. Glycine even begins to metabolize alcohol in the stomach.
Glycine helps moderate the blood sugar-raising effects of glucose (carbohydrates). Additionally, it enhances insulin efficiency without significantly raising insulin levels while increasing beneficial glucagon, insulin’s “counterpart.” This can help reduce high blood lipid levels associated with insulin resistance.
Glycine is a key component of collagen found in the skin. Collagen peptides, which are hydrating and rejuvenating, reduce wrinkles and improve skin elasticity due to their high glycine content. A small amount of glycine can also enhance alertness and improve circulation in cerebral microcapillaries.
Several studies have examined glycine’s effects on sleep in humans. They found that consuming glycine before bed improves sleep quality, aids falling asleep, and reduces early waking. Even with shorter sleep durations, glycine consumption can leave individuals feeling more refreshed.